A 45 year old male with HFPEF 2° to Alcoholism - wet beri beri,Acute infarct in PCA territory (Recurrent CVA),Acute hepatitis 2° to viral with CLD(resolving) AKI( Renal interstitial nephritis) ?Uremic Encephalopathy,Delirium with Alcohol dependence syndrome,chronic alcoholic and smoker,k/c/o HTN since 5months

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Here we discuss our individual patient's problems through series of inputs from available global online community of experts with an aim to solve those patient's clinical problems with collective current best evidence based inputs. 

This E log book also reflects my patient-centered online learning portfolio and your valuable inputs on the comment box is welcome.

Here is a case i have seen : 

A 45 yr old male patient who is auto driver by occupation came with 

C/o weakness of b/l upperlimb and lowerlimb since 1 week

C/o pedal edema since 1 week

HOPI:

Pt was apparently asymptomatic 1 week back then developed weakness of b/l upper and lower limb since then 

No h/o deviation of mouth ,giddiness,decreased urine output ,burning micturition ,facial puffiness

C/o swelling of b/l lower limbs upto knees which is pitting type

H/o sob present 

H/o palpitations present on exertion

No h/o fever ,cold ,cough

Past history:

K/c/o HTN since 5 months and on
tab metaprolol 50mg od
Tab hydroxychloroquine 12.5mg od

Not k/c/o Epilepsy ,CAD,Asthma,DM


Personal history:

Patient takes mixed diet, appetite normal,sleep adequate,bowel and bladder regular,chronic alcoholic since 20 years and takes 90-180ml/day,smoker


General examination:

Pt is drowsy,conscious
No pallor
No icterus
No cyanosis
No clubbing
No koilonychia
No lymphadenopathy
B/l pedal edema + upto knees which is pitting type 

Vitals- Temperature- Afebrile on touch
             PR- 79bpm
             RR- 18cpm
             BP- 180/110mmhg

Systemic examination:

CVS- S1S2 heard , no murmurs
RS- BAE present ,NVBS +
P/A - distended,no tenderness,no organomegaly,bs+
CNS- level of consciousness- drowsy
Cranial nerves- normal
Sensory system - not elicitable
Power- normal  
Tone - normal
Reflexes   B     T        S       K      A       P

  R-         2+       2 +    1+     2+    1+  extension
  L    -      2+      2+      1+     2+    1+  extension

Investigations-

Cbp:

Hb- 7.5
Tlc-13000
Plt-1.5 lakhs

BGT- 0+ve

Pt- 25sec
INR- 1.8
APTT- 49sec

BT- 2mins 30sec
CT- 5mins 30sec

Rbs-114

Serology- Negative

LFT- 

Tb-1.35
DB- 0.31
Ast- 1265
Alt- 1615
Alp-470
TP-5.5
Alb-3.4
A/G - 1.66

RFT- 

Urea- 180
Cr-5.5
Uric acid-13.0
Ca2+ -9.2
Phosphorus- 6.4
Na+ - 131
K+ - 4.5
Cl - 103

Spot urine protein -15
Spot urine crratinine- 19.2
Ratio - 0.78

Abg :

PH - 7.39
Pco2- 16.7
Pco2- 108
Hco3-  - 13.6

Cue:

Alb-1+

Pus cells- 10-12

Epithelial cells- 4-5

Sugars- nil

USG:


ECG-


Treatment:

IVF - NS,RL @100ml/hr

Tab.Ecospirin 75mg/po/od

Tab.Clopidogrel 75mg/po/od

Tab.Atorvastatin 40mg/po/od

Salt restricted diet <2.4g/day

Inj.Lasix 20mg/iv/bd

Tab.Benfomet 20mg/po/od

Bp charting 2nd hrly

Strict I/O charting hrly

Temperature charting 4th hrly

Tab.Nicardia 10mg/po/stat

Syp.Lactulose 15ml/po/bd

Syp.Hepamerz 15ml/po/bd

Inj.monocef 1g/iv/bd

Tab.Azithromycin500mg/po/od


DAY2:

No fresh complaints

O/E- pt is drowsy , oriented to person ,not oriented to time ,place

No Pallor 

Icterus present

No Cyanosis

No Clubbing

No koilonychia

No Lymphadenopathy

B/L pitting type pedal edema upto knees +

Temperature - Afebrile

PR- 102bpm

BP- 150/100mmhg

GRBS - 160mg/dl

I/O - 2000/1800 ml

CVS - S1S2 + ,JVP raised

RS - BAE+ 

P/A - Soft,non tender,bs sluggish

CNS -Pupils - B/L reacting to light       

Reflexes - B   T   S   K   A   P

R               3+ 2+ 1+ 2+ 1+ extension

L               2+ 2+ 1+ 2+ 1+ extension

Reffered to Psychiatry  i/v/o altered sensorium,hallucinations,self talk and chronic alcoholic since 20years 

Investigations: 

CBP-


CUE-


2D Echo-


Reticulocyte count -


Treatment:

IVF - NS,RL with thiamine 2amp(slow iv) u.o+35ml/hr

Tab.Ecospirin 75mg/po/od

Tab.Clopidogrel 75mg/po/od

Tab.Atorvastatin 40mg/po/od

Salt restricted diet <2.4g/day

Inj.Lasix 40mg iv/bd

Tab.Benfomet 20mg/po/od

Bp charting 2nd hrly

Strict I/O charting hrly

Temperature charting 4th hrly

Syp.Lactulose 15ml/po/bd

Syp.Hepamerz 15ml/po/bd

Inj.monocef 1g/iv/bd

Tab.Azithromycin500mg/po/od

Inform sos

Inj.vit k 10mg/iv/stat

Ducolex suppositories (2tab)

Tab.pregabalin 75mg

Inj.lorazepam 4mg (1amp/im/hs)if pt is not getting sleep after taking pregabalin

Inj.lorazepam 4mg(1amp/im/sos)if pt is iiritable 


DAY3:

No fresh complaints

O/E- pt is conscious,drowsy , oriented to person ,not oriented to time ,place

Icterus present

B/L pitting type pedal edema upto knees +

Temperature - febrile to touch

PR- 87bpm

RR - 17cpm

BP- 180/110mmhg 

Spo2- 97%@R.A

GRBS - 143mg/dl

I/O - 2000/1800 ml

CVS - S1S2 +

RS - BAE+ 

P/A - Soft,non tender,bs sluggish

CNS -pupils - B/L reacting to light       

Reflexes - B   T   S   K   A   P

R               3+ 2+ 1+ 3+ 1+   -

L               2+ 2+ 1+ 2+ 1+   -

Investigations: 

CBP-


CUE-


PT-


APTT-


Reticulocyte count -


Treatment:

IVF - NS,RL @u.o+30ml/hr

Inj.Thiamine 2amp in 100ml NS/ IV /BD

Tab.Aldactone 50mg/po/bd

Tab.Ecospirin (75/20mg)/po/hs

Tab.Clopidogrel 75mg/po/od

Tab.Atorvastatin 20mg/po/od

Tab.Cilnidipine 10mg/po/od

Salt restricted diet <2.4g/day

Inj.Lasix 20mg iv/bd

Bp charting 2nd hrly

Strict I/O charting hrly

Temperature /PR/Spo2charting 4th hrly

Syp.Lactulose 15ml/po/bd

Syp.Potchlor 15ml in 1 glass of water/po/bd

Syp.Hepamerz 15ml/po/od

Inj.monocef 1g/iv/bd

Tab.Azithromycin500mg/po/od

Tab.pregabalin 75mg

Inj.lorazepam 4mg (1amp/im/hs)if pt is not getting sleep after taking pregabalin

Inj.lorazepam 4mg(1amp/im/sos)if pt is iiritable 


DAY4:

No fresh complaints

O/E- pt is conscious,drowsy , not oriented to time ,place,person

No fever spikes

B/L pitting type pedal edema upto knees +

Temperature - Afebrile 

PR- 99bpm

RR - 17cpm

BP- 150/90mmhg 

GRBS - 158mg/dl

Spo2- 96%@R.A

I/O - 2850/1750 ml

CVS - S1S2 +,JVP raised 

RS - BAE+ , b/l fine crepts + ISA,IAA,MA

P/A - Soft,non tender

CNS- pupils - R -reacting to light  

              L- not reacting to light      

Reflexes - B   T   S   K   A   P

R               3+ 2+ 1+ 3+ 1+   -

L               2+ 2+ 1+ 2+ 1+   -

Investigations: 

CBP-


PT- 15sec

INR-1.11

APTT-30sec

ABG-

RFT-


LDH-


Treatment:

IVF - 1 RL @50ml/hr(slow iv)

Inj.Thiamine 2amp in 100ml NS/ IV /TID

Tab.Aldactone 50mg/po/bd

Tab.Ecospirin (75/20mg) H/S 

Tab.Cilnidipine 10mg/po/bd

Salt restricted diet <2g/day

Fluid restriction <2lit/day

Propped up posture 

Inj.Lasix 20mg iv/bd

Bp/Spo2-/PR charting 2nd hrly

Strict I/O charting hrly

Syp.Lactulose 15ml/po/hs

Syp.Potchlor 15ml in 1 glass of water/po/tid

Syp.Hepamerz 15ml/po/bd

Inj.monocef 1g/iv/bd

GRBS charting 8th hrly

Tab.pregabalin 75mg

Inj.lorazepam 4mg (1amp/im/hs)if pt is not getting sleep after taking pregabalin

Inj.lorazepam 4mg(1amp/im/sos)if pt is iiritable 


DAY 5:

O/E- pt is conscious,not coherent , oriented to person,not oriented to time ,place

Pt passed stools yesterday evening

B/L pitting type pedal edema upto knees +

Temperature - Afebrile 

PR- 98bpm

RR - 17cpm

BP- 160/100mmhg 

GRBS - 131mg/dl

Spo2- 96%@R.A

I/O - 2350/1300 ml

CVS - S1S2 +

RS - BAE+ , b/l fine crepts + ISA,IAA,MA

P/A - Soft,non tender

CNS- pupils - R -reacting to light  

              L- not reacting to light      

Reflexes - B   T   S   K   A   P

R               3+ 2+ 1+ 3+ 1+   -

L               2+ 2+ 1+ 2+ 1+   -

Investigations: 

CBP-


PT-15sec

APTT-30sec

INR-1.11

RFT-


LDH-


Coombs test- 


Treatment:

IVF - 1 RL @50ml/hr(slow iv)

Inj.Thiamine 2amp in 100ml NS/ IV /TID

Tab.Aldactone 50mg/po/bd

Tab.Ecospirin (75/20mg) H/S 

Tab.Cilnidipine 10mg/po/bd

Salt restricted diet <2g/day

Fluid restriction <2lit/day

Propped up posture 

Inj.Lasix 20mg iv/bd

Bp/Spo2-/PR charting 2nd hrly

Strict I/O charting hrly

Syp.Lactulose 15ml/po/hs

Syp.Potchlor 15ml in 1 glass of water/po/tid

Syp.Hepamerz 15ml/po/bd

Inj.monocef 1g/iv/bd

Temperature charting 4th hrly

Tab.pregabalin 75mg

Inj.lorazepam 4mg im


DAY 6:

O/E- pt is conscious,not coherent ,not oriented to time ,place,person

Pt passed stools 

Temperature - Afebrile 

PR- 98bpm

RR - 17cpm

BP- 180/90mmhg 

GRBS - 126mg/dl

Spo2- 96%@R.A

I/O - 12500/1000 ml

CVS - S1S2 +

RS - BAE+ , b/l fine crepts + ISA,IAA,MA

P/A - Soft,non tender

CNS- pupils - R -reacting to light  

              L- not reacting to light      

Investigations: 

CBP-


RFT-


Treatment:

IVF - 1 RL @50ml/hr(slow iv)

Inj.Thiamine 2amp in 100ml NS/ IV /TID

Tab.Aldactone 50mg/po/bd

Tab.Ecospirin (75/20mg) H/S 

Tab.Cilnidipine 10mg/po/bd

Salt restricted diet <2g/day

Fluid restriction <2lit/day

Propped up posture 

Inj.Lasix 40mg iv/bd

Bp/Spo2-/PR charting 2nd hrly

Strict I/O charting hrly

Syp.Lactulose 15ml/po/bd

Syp.Potchlor 15ml in 1 glass of water/po/tid

Syp.Hepamerz 15ml/po/bd

Inj.monocef 1g/iv/bd

Temperature charting 4th hrly

Tab.Arkamine 0.1mg od

Tab.pregabalin 75mg

Inj.lorazepam 4mg/im

Inj.Haloperidol 5mg im sos


DAY 7:

O/E- pt is drowsy but arousable,not coherent ,not oriented to time ,place,person

Temperature - Afebrile 

PR- 82bpm

RR - 17cpm

BP- 150/80mmhg 

GRBS - 126mg/dl

GCS-E4V5M6

Spo2- 96%@R.A

I/O - 1630/2800 ml

CVS - S1S2 +

RS - BAE+ ,NVBS

P/A - Soft,non tender

CNS- pupils - NSRL              

Investigations: 

CBP-

LFT-
RFT-


Treatment:

IVF - NS, RL u.o+ 30ml/hr

Inj.Thiamine 2amp in 100ml NS/ IV /TID

Tab.Aldactone 50mg/po/bd

Tab.Ecospirin (75/20mg) H/S 

Tab.Cilnidipine 10mg/po/bd

Salt restricted diet <2g/day

Fluid restriction <2lit/day

Propped up posture 

Inj.Lasix 40mg iv/bd

Bp/Spo2-/PR charting 2nd hrly

Strict I/O charting hrly

Syp.Lactulose 15ml/po/bd

Syp.Potchlor 15ml in 1 glass of water/po/tid

Syp.Hepamerz 15ml/po/bd

Inj.monocef 1g/iv/bd

Temperature charting 4th hrly

Tab.Arkamine 0.1mg od

Tab.pregabalin 75mg

Inj.lorazepam 2mg IM


Day8:

O/E- pt is drowsy but arousable,not coherent ,not oriented to time ,place,person

Temperature - Afebrile 

PR- 82bpm

RR - 17cpm

BP- 180/110mmhg 

GCS-E4V5M6,15/15

Spo2- 97%@R.A

I/O - 2000/2300 ml

CVS - S1S2 +

RS - BAE+ ,NVBS

P/A - Soft,non tender

CNS-

Power               R               L

UL                     2/5            2/5

LL                     2/5            2/5

Reflexes-  B       T       S       A      K       P

R               -         -        -       2+     2+      -

L               -         -        -       2+     2+      -        

Investigations: 

BGT - O+ve

Treatment:

IVF - NS, RL u.o+ 30ml/hr

Inj.Thiamine 2amp in 100ml NS/ IV /TID

Tab.Aldactone 50mg/po/bd

Tab.Ecospirin (75/75/20mg) H/S 

Tab.Cilnidipine 10mg/po/bd

Salt restricted diet <2g/day

Fluid restriction <2lit/day

Propped up posture 

Inj.Lasix 40mg iv/bd

Bp/Spo2-/PR/temp charting 4th hrly

Strict I/O charting hrly

Syp.Lactulose 25ml/po/bd

Syp.Potchlor 15ml in 1 glass of water/po/tid

Syp.Hepamerz 15ml/po/bd

Inj.monocef 1g/iv/bd

Tab.Arkamine 0.1mg od

Tab.pregabalin 75mg po

Inj.lorazepam 2mg IM BD

Inj.Haloperidol 5mg/im/sos(if pt is irritable)


Day9:

O/E- pt is drowsy but arousable,not coherent ,not oriented to time ,place,person

Temperature - Afebrile 

PR- 84bpm

RR - 18cpm

BP- 160/90mmhg 

GCS-E4V5M6,15/15

Spo2- 97%@R.A

I/O - 1750/2200 ml

CVS -S1S2 +

RS - BAE+ ,NVBS

P/A - Soft,non tender

CNS-pupils-NSRL

Power R               L

UL       3/5            3/5

LL        3/5           3/5

Reflexes- B    T       S     A     K      P

R               2+   2+    2+     2+    2+    flexion

L               2+   2+    2+     2+    2+    flexion       

Investigations: 

Cbp: Hb-8.3

         Tlc-16300

         Plt-1.68lakhs/cumm

Lft:

Tb- 2.9

Db-1.15

Ast-79

Alt-182

All phosphate- 314

Tp-5.8

Alb-3.1

RFT-:

Urea-118

UA-9.9

Cr-4.3

Na+ -137

K+ -5.5

Cl -103

Blood culture:

6


Treatment:

IVF - NS, RL u.o+ 30ml/hr

Inj.Thiamine 2amp in 100ml NS/ IV /TID

Tab.Aldactone 50mg/po/bd

Tab.Ecospirin (75/75/20mg) H/S 

Tab.Cilnidipine 10mg/po/bd

Salt restricted diet <2g/day

Fluid restriction <2lit/day

Propped up posture 

Inj.Lasix 40mg iv/bd

Bp/Spo2-/PR/temp charting 4th hrly

Strict I/O charting hrly

Syp.Lactulose 25ml/po/bd

Syp.Potchlor 15ml in 1 glass of water/po/tid

Syp.Hepamerz 15ml/po/bd

Inj.monocef 1g/iv/bd

Tab.Arkamine 0.1mg od

Tab.pregabalin 75mg po

Inj.lorazepam 4mg IM 

Inj.Haloperidol 5mg/im/sos(if pt is irritable)

Inj.Haloperidol 2.5mg/I'm/bd

Nebulization with salbutamol 6th hrly(2respules)


Day 10:

O/E- pt is not oriented to time ,place,person

Temperature - Afebrile 

PR- 82bpm

RR - 20cpm

BP- 170/90mmhg 

GCS-E4V5M6,15/15

Spo2- 97%@R.A

I/O - 2900/2500 ml

Grbs-114mg/dl

CVS -S1S2 +

RS- BAE+ ,NVBS

P/A - Soft,non tender

CNS-pupils-NSRL

Power      R             L

UL           3/5          3/5

LL           3/5          3/5


Reflexes- B      T     S     A     K     P

R               2+   2+   2+    2+   2+  flexion

L               2+   2+   2+    2+   2+  flexion       

Investigations: 

Cbp: Hb-8.3

         Tlc-16300

         Plt-1.68lakhs/cumm

Lft:

Tb- 2.9

Db-1.15

Ast-79

Alt-182

All phosphate- 314

Tp-5.8

Alb-3.1

RFT-:

Urea-118

UA-9.9

Cr-4.3

Na+ -137

K+ -5.5

Cl -103

Treatment:

IVF - NS, RL u.o+ 30ml/hr

Inj.Thiamine 2amp in 100ml NS/ IV /TID

Tab.Aldactone 50mg/po/bd

Tab.Ecospirin (75/75/20mg) H/S 

Tab.Cilnidipine 10mg/po/bd

Salt restricted diet <2g/day

Fluid restriction <2lit/day

Proppped up posture 

Inj.Lasix 40mg iv/bd

Bp/Spo2-/PR/temp charting 4th hrly

Strict I/O charting hrly

Syp.Lactulose 25ml/po/bd

Syp.Potchlor 15ml in 1 glass of water/po/tid

Syp.Hepamerz 15ml/po/bd

Inj.monocef 1g/iv/bd

Tab.Arkamine 0.1mg od

Tab.pregabalin 75mg po

Inj.lorazepam 4mg IM 

Inj.Haloperidol 5mg/im/sos(if pt is irritable)

Inj.Haloperidol 2.5mg/IM/bd


Day11:

O/E- pt is not oriented to time ,place,person

Temperature - Afebrile 

PR- 86bpm

RR - 18cpm

BP- 140/90mmhg 

GCS-E4V5M6,15/15

Spo2- 97%@R.A

I/O - 1500/2000 ml

Grbs-103mg/dl

CVS -S1S2 +

RS- BAE+ ,NVBS

P/A - Soft,non tender

CNS-pupils-NSRL

Power      R         L

UL           3/5      3/5

LL            3/5      3/5

Reflexes- B     T     S     A      K      P

R               2+   2+   2+   3+    2+   flexion

L.              2+   2+   2+    3+   2+   flexion       

Investigations: 

Cbp: Hb-8.5

         Tlc-9600

         Plt-1.93

Pt-14

Inr-1

Aptt-28

Cue:

Pus cells-plenty

Epithelial cells- 3-4

Sugars-nil

Albumin- +

RBC- 1-2

Abg:

Ph- 7.46

Pco2-25

Po2-94

Hco3-17.8

RFT:

Urea-145

UA-9.3

Cr-4.6

Na+ -135

K+ -5.4

Cl -104

Treatment:

IVF - NS, RL u.o+ 30ml/hr

Inj.Thiamine 2amp in 100ml NS/ IV /TID

Tab.Aldactone 50mg/po/bd

Tab.Ecospirin (75/75/20mg) H/S 

Tab.Cilnidipine 10mg/po/bd

Salt restricted diet <2g/day

Fluid restriction <2lit/day

Proppped up posture 

Inj.Lasix 40mg iv/bd

Bp/Spo2-/PR/temp charting 4th hrly

Strict I/O charting hrly

Syp.Lactulose 25ml/po/bd

Syp.Potchlor 15ml in 1 glass of water/po/tid

Syp.Hepamerz 15ml/po/bd

Inj.monocef 1g/iv/bd

Tab.Arkamine 0.1mg od

Tab.pregabalin 75mg po

Inj.lorazepam 4mg IM 

Inj.Haloperidol 5mg/im/sos(if pt is irritable)

Inj.Haloperidol 2.5mg/IM/bd


Day12:

O/E- pt is not oriented to time ,place,person

Temperature - Afebrile 

PR- 86bpm

RR - 20cpm

BP- 130/80mmhg 

GCS-E4V5M6,15/15

Spo2- 98%@R.A

I/O - 1750/2600 ml

CVS -S1S2 +

RS- BAE+ ,NVBS

P/A - Soft,non tender

CNS-pupils-NSRL

Power      R             L

UL           4+/5          4+/5

LL           4+/5          4+/5


Reflexes- B      T     S     A     K     P

R               2+   2+   2+    3+   2+  flexion

L               2+   2+   2+    3+   2+  flexion       

Treatment:

IVF - NS, RL u.o+ 30ml/hr

Inj.Thiamine 2amp in 100ml NS/ IV /TID

Tab.Aldactone 50mg/po/bd

Tab.Ecospirin (75/75/20mg) H/S 

Tab.Cilnidipine 10mg/po/bd

Salt restricted diet <2g/day

Fluid restriction <2lit/day

Proppped up posture 

Inj.Lasix 40mg iv/bd

Bp/Spo2-/PR/temp charting 4th hrly

Strict I/O charting hrly

Syp.Lactulose 15ml/po/bd

Syp.Hepamerz 15ml/po/bd

Tab.Arkamine 0.1mg od

Tab.pregabalin 75mg po

Inj.lorazepam 4mg IM 

Inj.Haloperidol 5mg/im/sos(if pt is irritable)

Inj.Haloperidol 2.5mg/IM/bd


Sleep charts:






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